What is what medication is incompatible with lactated ringers?

There are several medications that are known to be incompatible with lactated Ringer's solution. Some of these medications include:

  • Amphotericin B: Mixing amphotericin B with lactated Ringer's solution can cause precipitation of the drug, leading to blockages in the IV line and decreased drug efficacy.
  • Cisplatin: Cisplatin is known to interact with electrolytes in lactated Ringer's solution, resulting in the formation of insoluble complexes that can cause kidney damage and other adverse effects.
  • Doxapram: Doxapram can react with the calcium in lactated Ringer's solution, resulting in the formation of a precipitate that can clog IV lines.
  • Heparin: Mixing heparin with lactated Ringer's solution can lead to precipitation of the drug, reducing its effectiveness and causing potential harm to the patient. It is important for healthcare providers to be aware of these potential interactions and to consult with a pharmacist or other healthcare professional before administering medications in combination with lactated Ringer's solution.